Since 1991, Moshe Leon has served as a managing partner in the accounting firm of Leon, Orlitsky & Co. Under his management, the firm has become one of the ten largest firms in Israel. In February 1997 he was appointed director of the Prime Minister’s Office, and thereafter he was appointed as the CEO of the Prime Minister’s Office. During his service in the Prime Minister’s Office, he engaged in promoting the economic issues on the government’s agenda, including privatization.
In 2004 he was appointed head of a public committee that dealt with the examination of operation, management, budgeting and ownership of government hospitals. Its principal recommendation was to separate the hospitals from the State by way of corporatization or by turning them into companies. In 2008, he was appointed chairman of the Jerusalem Development Authority, and in 2018 he was elected mayor of Jerusalem.
Leon serves as chairman of the executive committee of the Thelma Yelin Foundation, chairman of the audit committee of the Israel Export Institute, director of Elbit Imaging, and is member of the board of trustees of the Wolf Foundation, and a member of the board of Yuval – the Israeli ensemble for Jewish music and cantorial music.